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Myoglobin in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of myoglobin, a protein found in muscle cells, in your blood serum. Myoglobin helps release oxygen to muscles during intense exercise or injury.

Quick summary

["Myoglobin levels can help diagnose muscle damage or conditions affecting oxygen delivery in muscles."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
83106-5
Short code
Myoglobin SerPl IA-mCnc
Synonyms
Myoglobin SerPl IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
70
Critical range
— – 200 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
83880
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like muscle pain, weakness, or cramping—especially after exercise, trauma, or conditions like rhabdomyolysis (severe muscle breakdown). It may also be checked in cases of suspected heart attack (though it’s not specific to cardiac events) or other muscle disorders.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. If you’re on blood thinners or have a history of bleeding disorders, let your provider know before the test.

What the Results Mean

Results are interpreted based on your symptoms, medical history, and other tests. Elevated levels may suggest muscle injury, inflammation, or conditions like myoglobinuria (myoglobin in urine), which can lead to kidney problems if severe.

Common Conditions Linked to Myoglobin Levels

High levels can occur with muscle injuries (e.g., strains, fractures), certain medications (e.g., statins), or metabolic disorders. Low levels are rare but may indicate muscle wasting or certain genetic conditions.

Reference range

Adult males: 20-70 μg/L; Females: 25-58 μg/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated myoglobin levels often prompt further testing, such as urine analysis for myoglobin or kidney function checks, to rule out complications like kidney failure. Your provider will guide next steps based on your overall health and test results.

Short name

Myoglobin Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–2 business days, depending on your lab. Follow up with your provider if you have questions or concerns before receiving them.
Can I eat or drink before this test?
You can eat and drink normally before the test unless instructed otherwise by your provider. Avoid alcohol or heavy meals 2 hours before the draw if your provider specifies it.
Is there any risk or discomfort with this test?
The test involves a small needle insertion, which may cause mild discomfort or bruising. Rarely, blood clots or infection can occur, but these are uncommon. If you’re nervous, ask about sedation options if available at your lab.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy