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Myoglobin, Urine

Published: August 9, 2026Updated: August 17, 2026

This test measures the presence of myoglobin, a protein found in muscle tissue, in your urine. It can help identify conditions that cause muscle damage or injury.

Quick summary

["Urine myoglobin testing helps detect muscle-related issues that may require further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2640-1
Short code
Myoglobin Ur Ql
Synonyms
Myoglobin Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
0
Ref high
70
Critical range
— – 200 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83880
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a urine myoglobin test if you have symptoms like muscle pain, weakness, or signs of kidney problems. It can also be used to monitor certain conditions, such as rhabdomyolysis (severe muscle breakdown), where myoglobin levels in urine can rise significantly.

What Does a Positive Result Mean?

Elevated myoglobin in urine may suggest recent muscle damage, inflammation, or other conditions affecting muscle tissue. However, a single test result isn’t always definitive, so your doctor may recommend additional tests or follow-ups.

How Is the Test Performed?

A small urine sample is collected, usually through standard urinalysis procedures. The sample is then analyzed in a lab to detect myoglobin levels. No special preparation is typically needed, but drinking plenty of water beforehand can help dilute urine for clearer results.

What Are Common Causes?

High urine myoglobin can result from muscle injuries (e.g., strains, fractures), intense exercise, certain medications, or metabolic disorders. It can also appear in conditions like sepsis or severe dehydration.

Reference range

Adult males: 20-70 μg/L; Females: 25-58 μg/LN/A

Specimen: urine

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Myoglobin

Frequently asked questions

What Are My Next Steps If My Results Are Abnormal?
If your urine myoglobin test is elevated, your doctor may order additional tests, such as blood tests or kidney function checks, to determine the underlying cause. They may also recommend rest, hydration, or other treatments depending on your symptoms.
How Often Should I Get This Test?
The frequency depends on your health condition and symptoms. Your doctor will guide you on whether this test is part of routine monitoring or needed only under specific circumstances.
Can I Drink Fluids Before the Test?
Yes, drinking plenty of water before the test can help ensure your urine is diluted, making it easier for the lab to analyze. However, avoid excessive fluid intake just before testing if your doctor has specific instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy