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N6-Acetyl-L-lysine/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A specialized urine test that measures N6-acetyl-L-lysine relative to creatinine, helping account for differences in urine concentration.

Quick summary

["This test evaluates urinary N6-acetyl-L-lysine in relation to creatinine and is usually interpreted by a specialist."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79634-2
Short code
N6-Ac-L-lys/Creat Ur-sRto
Synonyms
N6-Ac-L-lys/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This is a urine test measuring N6-acetyl-L-lysine, an acetylated form of the amino acid lysine. The result is compared with urine creatinine to help account for how concentrated or dilute the urine sample is.

Why might I need this test?

This specialized test may be ordered to evaluate amino acid or protein metabolism, particularly when an inherited metabolic condition is suspected. It is not usually part of routine screening and is generally interpreted along with other laboratory and clinical findings.

How is the test performed?

A urine specimen is collected according to the laboratory's instructions, either as a single sample or over a specified period. The laboratory measures N6-acetyl-L-lysine and creatinine and calculates their ratio.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional. If a timed collection is required, record all urine for the stated period and store it as directed. Do not change your diet or stop medicines unless the ordering clinician advises you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urinary N6-acetyl-L-lysine ratio

Frequently asked questions

What does the creatinine-adjusted ratio show?
It expresses the amount of urinary N6-acetyl-L-lysine relative to creatinine. This helps reduce the effect of variations in urine concentration.
Do I need to fast for this test?
Fasting is not usually required unless the ordering laboratory specifically says so. Tell the clinician about supplements, medications, and unusual dietary changes because these may affect the result.
Can this test diagnose a metabolic disorder?
No. An abnormal result must be interpreted with symptoms, medical history, other laboratory tests, and sometimes follow-up or genetic testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy