N-Acetylcysteine in Urine (24-Hour Collection)
This test measures the amount of N-acetylcysteine, a compound derived from cysteine, in your urine over a 24-hour period. It may be used to assess certain metabolic or detoxification processes.
["Understanding your urine N-acetylcysteine levels can help identify potential metabolic or health-related patterns."]
Key facts at a glance
- LOINC
- 104696-0
- Short code
- N-acetylglycine/Creat Ur-sRto
- Synonyms
- N-acetylglycine/Creat Ur-sRto
- Category
- glucose
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if they suspect conditions affecting your body’s ability to process certain substances, such as metabolic disorders, genetic conditions, or to monitor detoxification pathways. It could also be part of a broader evaluation for kidney function or exposure to toxins.
What to Expect Before the Test
You’ll need to collect all urine produced in a 24-hour period (typically from one morning to the next). Follow your provider’s instructions for collecting and storing the sample to ensure accuracy. Drink plenty of water to help flush your system, but avoid foods or supplements that might interfere with the test results.
What the Results Mean
Results are not typically provided as a single numeric range since this is a qualitative or semi-quantitative measure of excretion over time. Your provider will interpret the results in relation to your overall health, medical history, and symptoms. Elevated levels may suggest certain metabolic or detoxification challenges, while lower levels might indicate normal processing.
Common Conditions Monitored
This test is less commonly used for routine screening but may play a role in diagnosing or monitoring conditions like certain genetic metabolic disorders, detoxification pathway dysfunctions, or in research settings evaluating toxin exposure or metabolic health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Urine NAC (24h)
Frequently asked questions
What does my N-acetylcysteine level indicate?
How often will I need this test?
Can I modify my diet or take supplements before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy