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National Comprehensive Cancer Network (NCCN) Ovarian Symptom Index Questionnaire (OSI-18)

Published: August 9, 2026Updated: August 17, 2026

This questionnaire assesses how ovarian cancer symptoms affect your daily life, helping doctors track changes over time.

Quick summary

This tool helps monitor how ovarian cancer symptoms impact your quality of life and treatment response.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
70555-8
Short code
NATIONALCOMPREHENSIVECANCERNETWORKOVARIANSYMPTOMINDEXQUESTIONNAIRE18ITE
Synonyms
—
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
0.5 N/A – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
facit
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Questionnaire Measures

The NCCN OSI-18 evaluates 18 specific symptoms related to ovarian cancer, such as abdominal pain, bloating, fatigue, and changes in bowel habits. Each symptom is rated on a scale to measure severity and frequency, helping doctors understand your experience and adjust care as needed.

How It’s Used in Care

Doctors use this questionnaire regularly to track how symptoms progress or improve with treatment. It’s not a blood test but a way to gather detailed information about your symptoms to guide treatment decisions.

Who Might Use It

Healthcare providers use this questionnaire for patients with ovarian cancer or those at high risk. It’s especially useful for monitoring treatment side effects and symptom management during and after treatment.

What to Expect When Completing It

You’ll answer questions about how often and how severely you experience symptoms like bloating, pain, or fatigue. The answers help doctors compare your current symptoms to past ones to identify trends or improvements.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This questionnaire provides critical insights into how ovarian cancer symptoms affect your daily life. It helps doctors assess treatment effectiveness, adjust medications, and plan interventions to improve your well-being. Early detection of worsening symptoms can lead to timely medical adjustments, potentially improving outcomes.

Frequently asked questions

Why do doctors use this questionnaire?
Doctors use it to track how ovarian cancer symptoms change over time, especially during treatment. It helps them make informed decisions about care and ensures you’re getting the most effective support for your symptoms.
Is this questionnaire the same as a blood test?
No, this is a questionnaire—it’s a set of questions about your symptoms. It doesn’t involve bloodwork but provides detailed information about how ovarian cancer impacts your daily life.
How often should I complete this questionnaire?
Your doctor will tell you how often to complete it, but it’s often done regularly (e.g., weekly or monthly) to monitor symptom changes closely, especially during treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy