Urine Sodium Mass Concentration (24-hour collection)
This test measures the total amount of sodium (a key electrolyte) excreted in your urine over a full day. It helps assess how well your kidneys are balancing sodium levels in your body.
["Helps diagnose and monitor conditions affecting sodium balance, kidney function, and fluid retention."]
Key facts at a glance
- LOINC
- 53129-3
- Short code
- Na Urate Cry #/area UrnS HPF
- Synonyms
- Na Urate Cry #/area UrnS HPF
- Category
- electrolyte
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 3.5
- Ref high
- 7.2
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- microscopy-light-hpf
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Sodium is essential for nerve and muscle function, blood pressure regulation, and maintaining fluid balance. Chronic high or low sodium levels can lead to health issues like high blood pressure, kidney problems, or heart disease. A 24-hour urine sodium test provides a comprehensive picture of your body’s sodium excretion, which isn’t easily captured by a single blood or spot urine test.
When You Might Need This Test
Your doctor may recommend this test if you have symptoms like frequent urination, swelling (edema), high blood pressure, kidney disease, or if you’re on medications that affect sodium levels (e.g., diuretics). It’s also used to evaluate conditions like primary hyperaldosteronism or to monitor kidney function in certain chronic diseases.
How the Test Works
You’ll collect all your urine over a 24-hour period, typically starting after a clean void (first morning urine is often discarded). The sample is then sent to a lab for measurement. Sodium is measured in milligrams (mg) per 24-hour urine volume, often reported as mg/day.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to limit certain medications or foods that could affect sodium levels (like salt supplements). Always follow your doctor’s instructions precisely to ensure accurate results.
Reference range
NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
24-Hour Urine Sodium
Frequently asked questions
What does a high urine sodium level mean?
What does a low urine sodium level mean?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy