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Urine Sodium Mass Concentration (24-hour collection)

Published: August 9, 2026Updated: August 17, 2026

This test measures the total amount of sodium (a key electrolyte) excreted in your urine over a full day. It helps assess how well your kidneys are balancing sodium levels in your body.

Quick summary

["Helps diagnose and monitor conditions affecting sodium balance, kidney function, and fluid retention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
53129-3
Short code
Na Urate Cry #/area UrnS HPF
Synonyms
Na Urate Cry #/area UrnS HPF
Category
electrolyte
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-hpf
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Sodium is essential for nerve and muscle function, blood pressure regulation, and maintaining fluid balance. Chronic high or low sodium levels can lead to health issues like high blood pressure, kidney problems, or heart disease. A 24-hour urine sodium test provides a comprehensive picture of your body’s sodium excretion, which isn’t easily captured by a single blood or spot urine test.

When You Might Need This Test

Your doctor may recommend this test if you have symptoms like frequent urination, swelling (edema), high blood pressure, kidney disease, or if you’re on medications that affect sodium levels (e.g., diuretics). It’s also used to evaluate conditions like primary hyperaldosteronism or to monitor kidney function in certain chronic diseases.

How the Test Works

You’ll collect all your urine over a 24-hour period, typically starting after a clean void (first morning urine is often discarded). The sample is then sent to a lab for measurement. Sodium is measured in milligrams (mg) per 24-hour urine volume, often reported as mg/day.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to limit certain medications or foods that could affect sodium levels (like salt supplements). Always follow your doctor’s instructions precisely to ensure accurate results.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Sodium

Frequently asked questions

What does a high urine sodium level mean?
High urine sodium levels may indicate excessive sodium intake, kidney problems that impair sodium excretion, or conditions like Cushing’s syndrome or primary hyperaldosteronism. It can also signal dehydration or certain medications affecting sodium balance.
What does a low urine sodium level mean?
Low urine sodium levels can suggest excessive water retention (hyponatremia), kidney disease, or conditions like heart or liver failure that impair sodium excretion. It may also occur in patients on certain medications or with severe dehydration.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition, symptoms, and treatment plan. Regular monitoring may be recommended for chronic kidney disease, heart failure, or other long-term conditions affecting sodium balance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy