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Uric Acid, Serum Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of uric acid in your blood serum, a waste product from purine metabolism that can build up and contribute to conditions like gout or kidney stones.

Quick summary

["Uric acid levels help assess kidney function and risk for crystal-related diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
16257-8
Short code
Na Urate Cry Stone Ql IR
Synonyms
Na Urate Cry Stone Ql IR
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
infrared-spectroscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for kidney problems, diagnose gout, evaluate high-risk conditions (e.g., after chemotherapy), or monitor treatments for conditions like hyperuricemia.

What to Expect Before the Test

No special preparation is needed, but avoid heavy meals or alcohol 2 hours before testing. If you’re on medications (e.g., diuretics), discuss them with your provider to avoid potential fluctuations in results.

How the Test Works

A blood sample is drawn from a vein, typically in your arm. The serum is then analyzed to measure uric acid levels using a specialized lab technique.

What the Results Mean

Results are compared to general reference ranges, but individual ranges may vary by lab. High levels may signal kidney issues, gout, or metabolic disorders, while low levels could indicate liver or bone marrow problems.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Uric Acid

Frequently asked questions

What could cause elevated uric acid?
Elevated uric acid can result from diet (high-purine foods), kidney dysfunction, metabolic syndrome, or certain medications. It may also appear in conditions like psoriasis or hemolytic anemia.
What could cause low uric acid?
Low uric acid is less common but may occur with liver disease, certain genetic disorders, or excessive urate excretion. It’s rarely a standalone concern unless linked to other health issues.
Do I need to fast for this test?
No fasting is required, but avoid heavy meals or alcohol 2 hours before testing to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy