Serum Sodium and Potassium Electrolyte Profile (with Fractional Renin Activity)
This test measures key minerals in your blood (sodium and potassium) and assesses how your kidneys regulate them, including a measure of renin—a hormone involved in blood pressure and fluid balance.
["Helps diagnose and monitor conditions affecting your kidneys, blood pressure, or electrolyte balance."]
Key facts at a glance
- LOINC
- 54437-9
- Short code
- Na Urate MFr Stone IR
- Synonyms
- Na Urate MFr Stone IR
- Category
- electrolyte
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 3.5
- Ref high
- 7.2
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- infrared-spectroscopy
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Sodium and Potassium Do in Your Body
Sodium is essential for balancing fluids in your body and maintaining proper heart and muscle function. Potassium helps regulate heart rhythm and muscle contractions. Together, they work to keep your body’s fluid and electrolyte levels in balance.
How Renin Works in Your System
Renin is an enzyme produced by your kidneys that triggers a process to control blood pressure and fluid retention. Measuring renin helps doctors understand how well your kidneys are managing these functions, especially in conditions like high blood pressure or kidney disease.
When This Test Might Be Ordered
Your doctor may recommend this test if you have symptoms like high or low blood pressure, frequent urination, swelling, fatigue, or if you have a history of kidney problems, heart conditions, or hormonal imbalances.
Common Conditions This Test Helps Identify
This test can help diagnose or monitor conditions such as hypertension (high blood pressure), kidney disease, adrenal disorders, or metabolic imbalances. It may also be used to evaluate how well medications are working to manage these conditions.
Reference range
NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal sodium or potassium levels can cause serious health issues, including heart rhythm problems, muscle weakness, confusion, or even seizures. Renin levels help doctors determine if your kidneys are functioning properly to regulate blood pressure and fluid balance, which is critical for overall health.
Short name
Electrolyte Panel with Renin Measurement
Frequently asked questions
What does a high or low sodium or potassium level mean?
How does renin relate to kidney function?
Can diet affect the results of this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy