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Newborn Thyroid Screening Test, Dried Blood Spot

Published: August 9, 2026Updated: August 16, 2026

A newborn screening test that uses a dried blood spot to assess markers of thyroid function and help detect congenital thyroid disorders early.

Quick summary

["Early thyroid screening in newborns can identify possible thyroid problems that may require prompt treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54090-6
Short code
NB pnl Thyroid DBS
Synonyms
NB pnl Thyroid DBS
Category
thyroid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This newborn screening test checks a dried blood spot for markers of thyroid function, commonly thyroid-stimulating hormone and sometimes thyroxine. It helps detect thyroid disorders that may not be obvious from a baby's symptoms at birth.

Why might I need this test?

Thyroid screening is routinely offered to newborns because untreated thyroid deficiency can affect growth, brain development, and other health outcomes. The test is part of newborn screening and does not necessarily mean that a problem has been found.

How is the test performed?

A few drops of blood are collected from the baby's heel and placed on a filter-paper card, which is allowed to dry. The card is then sent to a laboratory for testing.

How do I prepare for the test?

No special preparation or fasting is usually needed. The blood sample is generally collected during the newborn period, and the heel may feel tender briefly after the finger-prick.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Newborn thyroid screen

Frequently asked questions

Does an abnormal result mean my baby has a thyroid disorder?
No. A screening result only indicates that further testing may be needed. A healthcare professional can arrange repeat or confirmatory testing before making a diagnosis.
Why is newborn thyroid screening important?
Thyroid hormone is important for normal growth and brain development. Early detection allows treatment to begin promptly if a thyroid disorder is confirmed.
Will my baby need a venous blood draw after screening?
Sometimes. If the dried blood spot result is abnormal or unclear, the baby may need repeat screening or a confirmatory venous blood test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy