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C-reactive protein (CRP) - High-Sensitivity

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when your body is fighting inflammation, often used to check for signs of infection, injury, or other inflammatory conditions.

Quick summary

["High CRP levels may signal inflammation needing further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71495-6
Short code
NETWORKCODE
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
esrd
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like fever, pain, or swelling, or if you’re at risk for conditions like heart disease, autoimmune disorders, or recent surgery. It’s also used to monitor chronic conditions like arthritis or kidney disease.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are usually reported in milligrams per liter (mg/L). Very low levels may indicate no inflammation, while higher levels could mean infection, injury, or other health issues. Your doctor will interpret results in the context of your overall health.

Common Conditions Monitored

High-sensitivity CRP helps track inflammation in conditions like rheumatoid arthritis, lupus, or after surgeries or trauma. It’s also used to assess cardiovascular risk.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

What does a high CRP level mean?
A high CRP level suggests inflammation is present, which could be due to infection, injury, or other inflammatory conditions. Your doctor will discuss next steps based on your symptoms and test results.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a heart-healthy diet, staying active, and managing stress may help lower inflammation over time.
How often should I get this test?
Your doctor will determine how often to check your CRP levels based on your health needs, such as monitoring chronic conditions or assessing risk for heart disease.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy