Neurofascin-155 IgG Antibody (Serum)
This test measures the level of antibodies against neurofascin-155, a protein found in the nervous system. These antibodies may be detected in conditions affecting nerve function or structure.
["This test helps evaluate potential nerve-related disorders by checking for abnormal immune responses."]
Key facts at a glance
- LOINC
- 100845-7
- Short code
- Neurofascin155 IgG4 Ser Ql FC
- Synonyms
- Neurofascin155 IgG4 Ser Ql FC
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may recommend this test if you have symptoms like numbness, weakness, or other neurological issues that could be linked to nerve damage or autoimmune activity. It may also be used in research or specialized diagnostic contexts for conditions like Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy (CIDP), or other neurological disorders involving nerve proteins.
What Does the Test Involve?
A blood sample is drawn from a vein in your arm. The serum portion of your blood is then tested for the presence of neurofascin-155 antibodies using an immunoassay method. This process detects whether your immune system has produced antibodies against this specific protein.
What Are Possible Results?
Results are qualitative (positive or negative) and indicate whether antibodies are present. A positive result suggests your immune system may be targeting neurofascin-155, which could be associated with certain nerve-related conditions. Your doctor will interpret the result in the context of your symptoms and medical history.
What Does This Test Mean for My Health?
Neurofascin-155 antibodies are not commonly measured in routine clinical practice. A positive result may raise suspicion for autoimmune nerve disorders but does not diagnose a specific condition alone. Further evaluation, including clinical assessment and possibly additional tests, will be needed to determine the cause of your symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Neurofascin-155 Antibodies in Neurology
Short name
Neurofascin-155 Antibody Test
Frequently asked questions
What are the normal reference ranges for this test?
How often will I need to retest if my results are positive?
Can this test be used to diagnose Guillain-Barré syndrome or other nerve disorders?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy