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Neuronal Protein in Cerebrospinal Fluid (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of proteins associated with nerve cells in your cerebrospinal fluid (CSF). It may help diagnose or monitor conditions affecting the brain and spinal cord.

Quick summary

["This test helps identify nerve-related issues in the brain and spinal fluid."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17336-9
Short code
Neuronal Ab Ser Ql IF
Synonyms
Neuronal Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

The test detects specific proteins linked to neurons (nerve cells). These proteins can be released into the CSF when nerve damage or disease occurs, such as in neurodegenerative disorders or traumatic brain injury.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like headaches, vision changes, numbness, weakness, or neurological issues that suggest nerve damage or brain/spinal cord conditions.

How Is the Sample Collected?

A small amount of cerebrospinal fluid is collected via a procedure called a lumbar puncture (spinal tap). A needle is inserted into your lower back to draw the fluid into a container.

What Does the Test Result Mean?

Results are interpreted by your doctor based on your symptoms and medical history. Elevated levels may indicate nerve damage or certain neurological diseases, while normal results suggest no significant abnormalities.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is particularly useful for diagnosing conditions like multiple sclerosis, Guillain-Barré syndrome, or other neurodegenerative diseases affecting nerve cells in the CNS. It can also help assess the extent of nerve injury post-trauma or during monitoring of chronic conditions.

Short name

Neuronal Protein CSF

Frequently asked questions

What Are Common Causes of Abnormal Results?
Abnormal results may occur due to nerve diseases, brain injuries, infections, or inflammatory conditions. Your doctor will consider your symptoms and medical history to determine the cause.
How Often Should I Get This Test?
The frequency depends on your symptoms, diagnosis, and treatment plan. Your doctor will advise you on how often to repeat this test based on your individual needs.
Is There Any Preparation Needed Before the Test?
No special preparation is required. You may be asked to empty your bladder before the procedure, but otherwise, you can eat and drink as usual.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy