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Neuropsychological Functioning Profile (Screening) – Serum/Plasma Substance Content

Published: August 9, 2026Updated: August 16, 2026

This test measures certain substances in your blood that may help assess how your brain chemistry supports cognitive functions like memory, attention, and reasoning. It’s often used as a preliminary check for conditions affecting the nervous system.

Quick summary

["A simple blood test to check for potential brain chemistry imbalances that could impact mental clarity and function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101030-5
Short code
Neuropsych H&P note
Synonyms
Neuropsych H&P note
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
neuropsychology
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Your blood sample will be analyzed for a range of neuroactive substances, including neurotransmitters (like dopamine and serotonin), neurotrophic factors (that support brain health), and metabolites (byproducts of brain activity). These substances play roles in mood, focus, and cognitive processing. The test uses a sensitive immunoassay method to detect these compounds at very low levels.

Why It’s Ordered

Your healthcare provider may recommend this test if you’re experiencing symptoms like persistent brain fog, difficulty concentrating, mood swings, or other signs of neurological or psychiatric concern. It can also be part of a broader evaluation for conditions like depression, ADHD, or neurological disorders.

Sample Collection and Preparation

You’ll have a small amount of blood drawn from a vein, usually in your arm. The blood is then separated into plasma or serum for testing. This process is quick and typically done in a clinical setting. You may feel slight discomfort, but it’s usually over quickly.

Test Results and Interpretation

Results are reviewed by a medical professional to compare against expected ranges for your age and health status. While this test doesn’t diagnose a specific condition, it can highlight imbalances that may warrant further investigation, such as additional blood tests, imaging, or specialized evaluations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Neuropsych Screening (Serum/Plasma)

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you once they’re ready to discuss the findings.
Can I eat or drink anything before this test?
For most neuropsychological substance screening tests, you can eat and drink normally before the blood draw. However, if your provider has specific instructions (such as fasting for other tests), follow those instead. Avoid alcohol for 24 hours before testing, as it may affect certain measurements.
Is this test covered by insurance?
Whether this test is covered by insurance depends on your specific diagnosis, insurance plan, and healthcare provider’s billing practices. Check with your insurance provider or your healthcare team to confirm coverage before scheduling the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy