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Neutrophil count (absolute, serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell that helps fight infections.

Quick summary

["Neutrophils are key defenders against bacteria and early signs of infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93354-9
Short code
Neut CD64 + Mono HLA DR Pnl Bld FC
Synonyms
Neut CD64 + Mono HLA DR Pnl Bld FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Neutrophils Do in Your Body

Neutrophils are a critical part of your immune system. They detect and destroy bacteria, fungi, and some viruses. When your body detects an infection, neutrophils rush to the site to help fight it off. High levels may indicate an active infection, while very low levels could suggest immune dysfunction or certain medical conditions.

When This Test Might Be Ordered

Your doctor may order this test if you have symptoms like frequent infections, fever, fatigue, or signs of inflammation. It’s also used to monitor conditions like leukemia, autoimmune diseases, or after treatments that affect the immune system.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and painless. If you’re on blood-thinning medication, let your doctor know before the test.

What the Results Mean

Results are typically reported as a count of neutrophils per microliter (µL) of blood. While reference ranges vary by lab, very high or very low counts can signal health concerns that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Neutrophil Count Variations

Short name

Neutrophil Level

Frequently asked questions

Why might my neutrophil count be higher than usual?
A high neutrophil count often means your body is fighting an infection, such as a bacterial illness, or responding to inflammation. It can also occur with stress, certain medications, or chronic conditions like rheumatoid arthritis. If your doctor suspects another cause, they may order additional tests.
Why might my neutrophil count be lower than usual?
Low neutrophil counts can indicate immune suppression, such as from chemotherapy, HIV/AIDS, or certain autoimmune diseases. It may also be linked to bone marrow disorders or nutritional deficiencies. If you notice frequent infections or fatigue, discuss your results with your doctor.
How often should I get this test?
This test is usually done as needed, depending on your symptoms or medical condition. Your doctor will determine how often you need it based on your individual health plan and ongoing care.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy