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Neutrophil Segment Count (Manual Differential Blood Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of mature neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections by attacking bacteria and other invaders.

Quick summary

["Neutrophils are key defenders against bacterial infections; their count helps doctors assess your immune response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98128-2
Short code
Neut.imm/Neut.segment Mar Manual - Rto
Synonyms
Neut.imm/Neut.segment Mar Manual - Rto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like frequent infections, fever, or signs of inflammation. It can also help diagnose conditions such as infections, autoimmune diseases, or blood disorders. Sometimes, it’s part of a routine blood check or to monitor treatment progress.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you may feel a brief pinch. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

The test result shows the percentage of neutrophils among all white blood cells. While reference ranges vary by lab, a higher-than-normal count may indicate infection or inflammation, while a lower count could suggest immune suppression or other conditions. Your doctor will interpret the results in the context of your overall health.

Common Conditions Monitored or Diagnosed

Neutrophil counts help diagnose or monitor conditions like bacterial infections, chronic inflammatory diseases (e.g., rheumatoid arthritis), or blood disorders (e.g., leukemia). They’re also used to evaluate how well treatments for infections or immune disorders are working.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormally high neutrophil counts may signal an active infection, stress, or inflammatory response. Low neutrophil counts can indicate immune deficiency, chemotherapy side effects, or other systemic illnesses. Your doctor will use these results alongside other symptoms and tests to guide diagnosis and treatment.

Short name

Manual Neutrophil Segment Count

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab and insurance. Some labs may offer faster turnaround for urgent cases.
Can I eat or drink before this test?
You can eat and drink normally before this test. No fasting is required.
Is there anything I should avoid before the test?
Avoid heavy exercise or strenuous activities 24 hours before the test. If you’re on blood-thinning medications, let your healthcare provider know before the draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy