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Neutrophil count (with differential breakdown: mature neutrophils, band neutrophils, and possibly other immature forms)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils in your blood and helps identify their maturity levels, which can indicate infection, inflammation, or other health conditions.

Quick summary

["Neutrophils are key white blood cells that fight infections; this test helps assess their presence and readiness to respond."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85376-2
Short code
Neut PMA DHR/Neut PMA NFr Bld FC
Synonyms
Neut PMA DHR/Neut PMA NFr Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is a Neutrophil Count?

Neutrophils are a type of white blood cell that plays a crucial role in defending your body against bacterial infections. This test measures the total number of neutrophils and, in some cases, breaks them down into different maturity stages (e.g., mature neutrophils vs. band neutrophils). The results help doctors understand if your immune system is responding normally to infections or if there may be an underlying issue.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like frequent infections, fever, fatigue, or signs of inflammation. It can also be used to monitor conditions such as leukemia, autoimmune diseases, or infections like sepsis. Sometimes, it’s part of routine blood work to check overall health.

How Is the Test Performed?

A small sample of your blood is drawn from a vein, usually in your arm. The blood is then analyzed in a lab to count neutrophils and assess their maturity. If the test includes a differential, it may require additional processing to separate and count different neutrophil types.

What Do the Results Mean?

Results are typically reported as a count of neutrophils per microliter of blood. A high neutrophil count (neutrophilia) may suggest infection, inflammation, or other conditions like stress or certain cancers. A low count (neutropenia) could indicate immune suppression, infections, or blood disorders. Your doctor will interpret the results in relation to your symptoms and overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Neutrophil count with differential

Frequently asked questions

Why do doctors care about neutrophil counts?
Doctors use neutrophil counts to diagnose infections, especially bacterial ones, and to monitor conditions that affect white blood cell production or function. For example, very low neutrophil counts can increase the risk of severe infections, while very high counts may point to chronic inflammation or other systemic issues. The differential helps identify if immature neutrophils are present, which can signal conditions like left shift (often seen in severe infections).
What if my results are outside the normal range?
If your results are abnormal, your doctor will discuss them with you and may recommend further testing or treatments. For example, if you have neutropenia, they might suggest adjusting medications, improving infection prevention strategies, or investigating underlying causes like autoimmune diseases or blood disorders. If you have neutrophilia, they may look for signs of infection or other conditions that require treatment.
Can I affect my neutrophil count?
Yes, certain factors can temporarily affect neutrophil counts, such as stress, illness, or certain medications (e.g., chemotherapy, steroids). Avoiding infections, managing stress, and following your doctor’s advice for medications can help support your immune system. If you suspect your medications are affecting your count, talk to your doctor about adjusting them or exploring alternatives.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy