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Neutrophil Count (with Differential Analysis) - Peripheral Blood

Published: August 9, 2026Updated: August 17, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood and may include a breakdown of their proportions (differential count).

Quick summary

["Neutrophils help fight infections and can indicate inflammation or infection in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
85375-4
Short code
Neut.PMA stim.DHR MFI Cont Bld FC
Synonyms
Neut.PMA stim.DHR MFI Cont Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
84484
SNOMED
302774002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Neutrophils Do in Your Body

Neutrophils are a key part of your immune system. They quickly respond to infections, such as bacterial ones, by moving to the site of infection and destroying harmful bacteria. High levels may suggest an active infection or inflammation, while low levels could indicate immune system issues or certain medical conditions.

How the Test Works

Blood is drawn from a vein, typically in your arm. A small sample is analyzed to count neutrophils and sometimes their subtypes (differential count). This helps healthcare providers assess immune function and identify potential health concerns.

When You Might Need This Test

Doctors may order this test to diagnose or monitor conditions like infections (e.g., pneumonia, urinary tract infections), inflammatory diseases (e.g., rheumatoid arthritis), or blood disorders. It can also be used during chemotherapy or other treatments that affect white blood cells.

Possible Results and Their Meaning

Results are usually reported as a count of neutrophils per microliter of blood. High neutrophil counts may signal infection, stress, or certain cancers. Low counts could indicate immune suppression, autoimmune diseases, or blood disorders. Always discuss results with your healthcare provider.

Reference range

Adult: 10-40 U/LN/A

Specimen: whole-blood

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Neutrophil Count

Frequently asked questions

Why might my doctor want to check my neutrophil count?
Your doctor may order this test to check for infections, inflammation, or immune system problems. It can also help monitor conditions like leukemia, autoimmune diseases, or reactions to medications that affect white blood cells.
What does a high neutrophil count mean?
A high neutrophil count often means your body is fighting an infection or responding to inflammation. It can also occur with stress, certain cancers, or long-term illnesses. Your doctor will consider your full medical history and other test results to understand the cause.
Can a low neutrophil count be dangerous?
Yes, a very low neutrophil count (neutropenia) can increase your risk of infections because your immune system is weakened. This is serious and requires immediate medical attention. Your doctor may adjust treatments or prescribe additional support if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy