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Neutrophil count (absolute) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood serum or plasma. Neutrophils help fight infections.

Quick summary

["Neutrophils are key defenders against bacterial infections; their count helps assess immune function and infection risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45150-0
Short code
Neutrophil Ab Ser IA-aCnc
Synonyms
Neutrophil Ab Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to evaluate your immune system, detect infections (especially bacterial), or monitor conditions like inflammation, autoimmune diseases, or certain cancers. It’s also used to guide treatment decisions, such as adjusting medications that suppress the immune system.

What to Expect Before the Test

No special preparation is needed for this test. You’ll provide a blood sample, typically drawn from a vein in your arm. If you’re on blood-thinning medications, let your provider know before the test.

What the Results Mean

Results are reported as the absolute number of neutrophils per microliter (µL) of blood. A higher-than-normal count may indicate infection, inflammation, or other conditions. A lower-than-normal count could signal immune suppression, infections, or certain medical treatments.

Common Conditions Affecting Neutrophil Levels

Elevated neutrophil counts may be seen in bacterial infections, chronic inflammation, stress, or conditions like leukemia. Low neutrophil counts can occur with immune deficiencies, certain cancers, or medications that weaken the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Absolute Neutrophil Count (Serum/Plasma)

Frequently asked questions

What does a high neutrophil count suggest?
A high neutrophil count often signals an active bacterial infection, inflammation, or stress response. It may also appear in conditions like acute appendicitis, severe dehydration, or certain autoimmune diseases. Your provider will consider your symptoms and other test results to interpret the cause.
What does a low neutrophil count mean?
A low neutrophil count (neutropenia) can indicate a weakened immune system, which increases the risk of infections. Causes may include chemotherapy, autoimmune diseases, certain medications, or genetic disorders. If you have frequent infections or symptoms like fever, seek medical attention promptly.
How often should I get this test?
The frequency depends on your health condition and treatment plan. If you have a chronic illness (e.g., cancer, autoimmune disease), your provider may order this test regularly to monitor your immune status. For routine check-ups or acute symptoms, it’s usually not part of standard testing unless indicated.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy