Skip to content

Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by white blood cells, particularly neutrophils, which can help assess kidney function and injury.

Quick summary

["NGAL helps monitor kidney health and response to illness or injury."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17348-4
Short code
Neutrophil IgA Ser-aCnc
Synonyms
Neutrophil IgA Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is NGAL Used For?

NGAL is often used to evaluate kidney function, especially in patients with conditions like acute kidney injury (AKI), heart failure, or infections. It can also be checked after surgeries or trauma to track recovery.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is tested for NGAL levels using a specialized immunoassay method.

When Might You Need This Test?

Your doctor may order this test if you have symptoms of kidney problems, such as swelling, fatigue, or changes in urine output. It may also be used in monitoring patients with chronic illnesses or after medical procedures.

What Do Results Mean?

Elevated NGAL levels may indicate kidney damage or stress, while lower levels might suggest normal kidney function or less severe injury. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: NGAL is a biomarker that reflects kidney injury and inflammation. It rises quickly in response to damage, making it useful for early detection of kidney problems in high-risk patients, such as those with severe infections, heart disease, or dehydration.

Short name

NGAL Serum/Plasma

Frequently asked questions

Why might my doctor order this test if I don’t have kidney issues yet?
Your doctor may use NGAL testing as a preventive or monitoring tool, especially if you have conditions like heart disease, diabetes, or recent surgery. It helps track how your body responds to stress or illness over time.
Can NGAL levels change based on what I eat or drink?
Dietary factors like salt intake or hydration status can influence kidney function indirectly, but NGAL itself is primarily a marker of cellular response to injury. Your doctor will consider these factors when evaluating results.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on lab processing times and your healthcare provider’s workflow.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy