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Neutrophil Count in Serum (Absolute Neutrophil Count, ANC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood serum. Neutrophils help fight infections by attacking bacteria and other invaders.

Quick summary

["Neutrophils are key defenders against bacterial infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17350-0
Short code
Neutrophil IgM Ser-aCnc
Synonyms
Neutrophil IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for infections, blood disorders, or immune system issues. It’s often used when you have symptoms like fever, fatigue, or unexplained bruising. Neutrophils can also rise or drop in response to certain medications or conditions like cancer.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a simple blood draw from a vein in your arm. The test is quick and usually painless. If you’re on blood-thinning medication, let your provider know.

What the Results Mean

Results are compared to your baseline or general reference ranges for healthy adults. Very high or very low neutrophil counts may indicate infections, immune disorders, or other health problems. Your provider will discuss findings in the context of your symptoms and medical history.

Common Conditions Linked to Neutrophil Counts

Low neutrophil counts (neutropenia) can make you more prone to infections, especially from bacteria. High neutrophil counts may signal acute infections, inflammation, or stress responses. Chronic conditions like leukemia or autoimmune disorders can also affect neutrophil levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Neutrophils are the body’s first responders to bacterial infections. Their count helps doctors diagnose or monitor conditions like sepsis, chronic infections, or blood cancers. Abnormal levels may also signal underlying immune dysfunction or reactions to treatments.

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

What causes a low neutrophil count?
Low neutrophil counts can result from infections, certain medications (like chemotherapy), autoimmune diseases, or genetic disorders. Stress, malnutrition, or liver/kidney problems may also play a role.
What causes a high neutrophil count?
High neutrophil counts often appear during acute infections (e.g., pneumonia, urinary tract infections) or severe inflammation. Stress, trauma, or certain cancers (like leukemia) can also elevate them.
Can diet affect neutrophil counts?
Diet may indirectly influence neutrophil levels—nutrient deficiencies (e.g., vitamin B12, folate) or excessive stress can affect white blood cell production. A balanced diet supports overall immune function but doesn’t directly alter neutrophil counts alone.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy