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Absolute Neutrophil Count (from Whole Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections and inflammation.

Quick summary

["Neutrophils are key defenders against bacterial infections; low counts may signal immune issues or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26499-4
Short code
Neutrophils # Bld
Synonyms
Neutrophils # Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like frequent or severe infections, fatigue, or signs of an immune disorder. It’s also checked before certain treatments (e.g., chemotherapy) to monitor your immune system’s strength.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw a blood sample. The process takes just a few minutes, and you may feel a slight pinch.

What the Results Mean

Results are compared to your baseline or general reference ranges for healthy adults. Very high or very low counts can signal health concerns, but interpretation depends on your overall health and symptoms.

Common Causes of Abnormal Results

Low neutrophil counts (neutropenia) may occur due to infections, certain medications, autoimmune diseases, or blood disorders. High counts could indicate inflammation, stress, or infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

What does a low neutrophil count mean?
A low neutrophil count (below normal) may mean your immune system isn’t working as well as it should, increasing your risk of infections. This could be due to medications, blood disorders, or other health conditions.
How often should I get this test?
Your doctor will determine how often you need this test based on your symptoms, medical history, and treatment plan. Regular monitoring may be needed if you have chronic conditions or are undergoing treatments that affect your immune system.
Can diet affect neutrophil counts?
While diet doesn’t directly change neutrophil counts, certain foods (like those high in vitamin B12, folate, or iron) support blood cell production. Avoiding extreme diets or supplements without medical advice is best.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy