Neutrophil Count in Cerebrospinal Fluid (CSF)
This test measures the number of neutrophils, a type of white blood cell, in your cerebrospinal fluid (CSF). It helps assess conditions affecting the brain and spinal cord.
["Neutrophils in CSF can signal inflammation or infection in the central nervous system."]
Key facts at a glance
- LOINC
- 754-2
- Short code
- Neutrophils # CSF Auto
- Synonyms
- Neutrophils # CSF Auto
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may order this test if you have symptoms like severe headaches, neck stiffness, fever, confusion, or neurological issues. It’s often used to check for conditions such as meningitis, brain infections, or other inflammatory diseases in the central nervous system.
What to Expect Before the Test
You’ll likely have a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is usually quick and may cause mild discomfort. No special preparation is needed, but inform your doctor about any medications or allergies.
What the Results Mean
High neutrophil counts in CSF often indicate an infection (e.g., bacterial meningitis) or severe inflammation. Low or normal counts may suggest viral infections, autoimmune conditions, or other non-infectious causes. Results are interpreted by your doctor based on your symptoms and medical history.
Common Conditions Linked to Abnormal Results
Elevated neutrophils in CSF are commonly associated with bacterial meningitis, subarachnoid hemorrhage, or certain brain abscesses. Lower-than-normal counts might suggest viral meningitis, multiple sclerosis, or other neurological disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Neutrophils
Frequently asked questions
How often will I need this test?
Can I eat or drink before the test?
What are the risks or side effects of this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy