Neutrophil Count in Cerebrospinal Fluid (CSF)

What Is This Test Measuring?

Neutrophils are a type of immune cell that fight infections. In the CSF, their presence can indicate conditions such as bacterial meningitis, certain infections, or inflammatory processes. This test is often used to diagnose or monitor these conditions.

When Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like severe headache, neck stiffness, fever, confusion, or neurological issues. It may also be done during diagnostic evaluations for suspected meningitis, encephalitis, or other central nervous system infections.

What Does a High or Low Neutrophil Count Mean?

A high neutrophil count in CSF is often associated with bacterial infections (e.g., bacterial meningitis) or severe inflammatory responses. A low count may suggest viral infections, autoimmune conditions, or other non-infectious causes. Your results will be interpreted in the context of your symptoms and medical history.

How Is This Test Done?

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). The sample is then analyzed under a microscope to count the neutrophils. This test is typically performed in a clinical laboratory.