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Neutrophil count (qualitative or semi-quantitative differential count from blood smear)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates the proportion of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections and inflammation.

Quick summary

["Neutrophils are key defenders against bacterial infections; their levels can signal health risks or conditions like infections or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40536-5
Short code
Neutrophils NFr DiafP Manual
Synonyms
Neutrophils NFr DiafP Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
10
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
82105
SNOMED
394971007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent infections, unexplained fevers, or signs of inflammation. It could also be part of routine blood work to monitor chronic conditions.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. The process takes about 5 minutes.

What the Results Mean

Results are qualitative or semi-quantitative, meaning they describe the relative proportion of neutrophils compared to other white blood cells. High levels may indicate infection or inflammation, while low levels could suggest immune suppression or other conditions.

Common Conditions Affecting Neutrophils

Elevated neutrophil counts might be seen in bacterial infections, certain cancers, or inflammatory diseases. Low neutrophil counts could be linked to autoimmune disorders, chemotherapy, or other immune system issues.

Reference range

Normal: <10 ng/mLN/A

Specimen: serum

No special preparation required. For PSA, avoid sexual activity for 24-48 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Neutrophils play a critical role in the body’s immune response. Their count helps diagnose infections, inflammation, or conditions affecting white blood cell function, guiding treatment decisions.

Short name

Neutrophil Differential

Frequently asked questions

What causes my neutrophil count to change?
Neutrophil levels can rise due to infections (like bacterial illnesses), stress, or certain medications. They may drop due to immune disorders, chemotherapy, or conditions that weaken the bone marrow.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times.
Can diet or supplements affect neutrophil counts?
Dietary changes or supplements rarely directly alter neutrophil counts, but they may influence overall immune health indirectly. Always discuss any supplements with your provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy