Neutrophil count (qualitative manual differential in whole blood)
This test evaluates the proportion of neutrophils, a type of white blood cell, in your blood using a manual microscopic count. It helps assess immune function and identify infections or inflammatory conditions.
["Neutrophils are key defenders against bacterial infections; abnormal counts may signal health concerns."]
Key facts at a glance
- LOINC
- 12238-2
- Short code
- Neutrophils NFr Fld Manual
- Synonyms
- Neutrophils NFr Fld Manual
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- manual-count
- CPT
- 86430
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order this test to diagnose or monitor conditions like infections (e.g., bacterial), inflammatory diseases, or blood disorders. It can also help evaluate responses to treatments or assess immune system function.
What to Expect Before the Test
No special preparation is needed. You may have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.
How the Results Are Interpreted
Results are qualitative (not a single number) and compare your neutrophil proportion to expected ranges for healthy adults. High or low proportions may indicate infection, immune issues, or other health problems.
Common Conditions Linked to Neutrophil Levels
Elevated neutrophils often signal acute bacterial infections, stress, or inflammation. Low neutrophils may point to immune deficiencies, autoimmune diseases, or certain medications. Always discuss results with your doctor.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Neutrophils play a critical role in fighting bacterial infections. Their count helps doctors identify whether your immune system is responding to illness or if there’s an underlying condition affecting white blood cell production or function.
Short name
Neutrophil differential (manual)
Frequently asked questions
What does a manual neutrophil differential tell me about my health?
Is fasting required for this test?
How long will I have to wait for my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy