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Neutrophil count (absolute)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections by attacking bacteria and other invaders.

Quick summary

["Neutrophils are key defenders against infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30454-3
Short code
Neutrophils NFr Pcar
Synonyms
Neutrophils NFr Pcar
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order an absolute neutrophil count to diagnose or monitor conditions like infections, certain cancers (e.g., leukemia), autoimmune diseases, or after treatments that suppress the immune system. It can also help assess how well your body is responding to treatment.

What to Expect Before the Test

This test is usually done by taking a small blood sample from a vein in your arm. You may feel a slight pinch, but it’s quick and doesn’t require special preparation. If you’re on blood-thinning medication, let your provider know before the test.

What the Results Mean

Results are reported as the number of neutrophils per microliter (µL) of blood. While reference ranges vary by lab, very low counts (below normal) may indicate infections, immune disorders, or bone marrow problems. Very high counts (above normal) could signal chronic infections, inflammation, or other conditions.

Common Conditions Affecting Neutrophils

Low neutrophil counts (neutropenia) might be linked to conditions like aplastic anemia, certain medications, or genetic disorders. High neutrophil counts (neutrophilia) can result from infections, stress, or inflammatory diseases. Your provider will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Neutrophils play a critical role in fighting bacterial infections. Abnormal counts can signal underlying health issues, such as immune deficiencies, infections, or side effects from treatments. Regular monitoring may be needed if you have chronic conditions like cancer or autoimmune diseases.

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

What causes a low neutrophil count?
Low neutrophil counts can result from infections, certain medications (like chemotherapy), autoimmune diseases, or genetic disorders. It may also occur after blood loss or severe stress. If you notice frequent infections or fatigue, discuss this with your doctor.
What should I do if my neutrophil count is high?
High neutrophil counts often point to infections, inflammation, or stress. If you have symptoms like fever, persistent fatigue, or unexplained weight loss, see your provider. They may recommend further testing or treatments to address the underlying cause.
Can diet or lifestyle affect neutrophil counts?
Diet and lifestyle can influence white blood cell counts indirectly. Staying hydrated, eating a balanced diet rich in vitamins (like vitamin C and zinc), and avoiding excessive stress may support immune health. However, diet alone won’t change neutrophil levels—your provider’s guidance is key.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy