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Neutrophil count (qualitative or semi-quantitative evaluation of neutrophil granulocyte levels)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence and relative proportion of neutrophils, a type of white blood cell, in your blood. It helps assess immune function and detect infections or inflammatory conditions.

Quick summary

["Neutrophils are key defenders against bacterial infections and inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68426-6
Short code
Neutrophils NFr Vitf Manual
Synonyms
Neutrophils NFr Vitf Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Neutrophils are a type of white blood cell that play a critical role in fighting off bacterial infections and responding to inflammation. This test evaluates their count and proportion in your blood sample, often done manually for qualitative or semi-quantitative assessment.

Why It’s Done

Doctors may order this test to diagnose or monitor conditions such as infections (e.g., bacterial), inflammatory diseases, or immune disorders. It can also help evaluate responses to treatments or identify risks for complications like sepsis.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The sample is processed manually to count and assess the proportion of neutrophils, which may involve staining techniques or microscopic examination.

What to Expect Before the Test

No special preparation is usually needed, but avoid strenuous activity or eating heavy meals 1–2 hours before the blood draw. If you’re on certain medications (e.g., steroids), inform your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High neutrophil counts may indicate acute infections, inflammation, or stress responses. Low counts could signal immune deficiencies, chronic infections, or certain medications. Abnormal proportions may also suggest underlying conditions like leukemia or autoimmune diseases.

Short name

Neutrophil evaluation

Frequently asked questions

What does a high neutrophil count mean?
A high neutrophil count often signals an active infection (e.g., bacterial), severe inflammation, or a stress response to illness or injury. Your doctor may recommend further testing to identify the cause.
Can diet affect neutrophil counts?
Dietary factors may indirectly influence immune function, but they rarely directly alter neutrophil counts. Focus on balanced nutrition to support overall immune health, but avoid relying on diet alone for test results.
When should I ask my doctor about this test?
Ask your doctor if you have symptoms like frequent infections, unexplained fatigue, or signs of inflammation (e.g., fever, swelling). If you’re undergoing treatment for a suspected immune or inflammatory condition, this test may be part of your monitoring.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy