Neutrophil Count (Manual Blood Cell Differential)

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for infections, inflammation, or other conditions that affect your immune system. It can also help diagnose or monitor certain blood disorders, such as leukemia or other cancers. Sometimes, it’s used to assess how your body responds to treatments for these conditions.

What to Expect Before the Test

You won’t need any special preparation for this test. A healthcare professional will take a small blood sample from a vein, usually in your arm. This is a quick and painless procedure, and you may feel a slight pinch or sting. The process usually takes a few minutes.

What the Test Results Mean

Neutrophil counts are typically reported as a percentage of your total white blood cell count or as an absolute number (count per microliter of blood). While reference ranges can vary by lab, a normal count is usually between 2,000 and 7,500 cells per microliter. However, your specific results will be interpreted by your healthcare provider based on your overall health and medical history.

Common Conditions Affecting Neutrophil Levels

High neutrophil counts (neutrophilia) may indicate infections, inflammation, or stress. Low neutrophil counts (neutropenia) can be linked to infections, autoimmune diseases, certain medications, or blood disorders. Your provider will discuss these findings with you in detail.