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Neutrophil Count (Absolute Neutrophil Count, ANC) in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections.

Quick summary

["Your ANC helps doctors assess your immune system’s ability to fight infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72345-2
Short code
Neutrophils/Rnd cells NFr Prost fld Man
Synonyms
Neutrophils/Rnd cells NFr Prost fld Man
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
86592
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Neutrophil Count Used For?

Neutrophils are a key part of your immune system. They help your body fight off bacteria and other infections. Your ANC helps doctors determine if your immune system is functioning well, especially if you have conditions like cancer, chemotherapy, or certain infections that may lower your white blood cell count.

Why Might Your Doctor Order This Test?

Your doctor may order an ANC test to check for infections, monitor immune function, or evaluate how treatments like chemotherapy or radiation are affecting your blood cells. It’s also useful before surgeries or if you have symptoms like frequent infections, fever, or fatigue.

How Is the Test Done?

A small amount of blood is drawn from a vein, usually in your arm. The blood is then analyzed in a lab to count the number of neutrophils. This is a quick and painless procedure.

What Are Common Results and What Do They Mean?

Results are typically reported as a count of neutrophils per microliter (µL) of blood. A lower than normal ANC may indicate an increased risk of infections, while a higher than normal count could suggest inflammation or other conditions. Your doctor will interpret the results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Neutrophils and Immune Function

Short name

ANC

Frequently asked questions

What does a low ANC mean?
A low ANC (below normal levels) can mean your immune system is weakened, making you more susceptible to infections. This can happen due to treatments like chemotherapy, certain medications, or underlying health conditions like leukemia or HIV. Your doctor may recommend preventive measures or adjustments to your treatment plan.
What does a high ANC mean?
A high ANC may indicate an infection, inflammation, or other conditions like autoimmune diseases. It can also be a reaction to stress or certain medications. Your doctor will look at other symptoms and test results to determine the cause.
How often should I get this test?
The frequency depends on your health condition and treatment plan. If you have a chronic illness or are undergoing treatment like chemotherapy, your doctor may order this test regularly to monitor your blood cell counts. Always follow your healthcare provider’s recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy