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Neutrophil count (manual differential)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections by attacking bacteria and other harmful substances.

Quick summary

["Neutrophils are key defenders against infections and inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
762-5
Short code
Neutrophils # Ur Manual
Synonyms
Neutrophils # Ur Manual
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for signs of infection, inflammation, or other blood-related conditions. It could also be used to monitor certain treatments or conditions, like autoimmune diseases or blood disorders, that affect white blood cell counts.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein (usually in your arm) to draw a blood sample. This is a quick and painless procedure, often done in a lab or clinic.

What the Test Results Mean

The test result shows the number of neutrophils per microliter of blood. While reference ranges can vary by lab, abnormal counts may indicate infections, certain cancers, or other health issues. Your provider will interpret the results in the context of your overall health.

Common Conditions Monitored

High neutrophil counts may signal infections, stress, or inflammatory conditions, while low counts could suggest immune deficiencies, infections, or certain medications. Your provider will use these results to guide diagnosis and treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Neutrophil count

Frequently asked questions

What does a high neutrophil count mean?
A high neutrophil count may indicate an active infection, such as bacterial infections, or conditions causing chronic inflammation. It can also be seen in stress or certain medications.
What does a low neutrophil count mean?
A low neutrophil count may mean your body has trouble fighting off infections. This can happen with certain blood disorders, immune system issues, or after treatments like chemotherapy.
How often should I get this test?
Your provider will determine how often you need this test based on your health condition, treatment plan, or symptoms. Regular monitoring may be needed if you have ongoing health issues affecting neutrophils.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy