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Neutrophil Count in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your cerebrospinal fluid (CSF). Neutrophils help fight infections.

Quick summary

["Neutrophils in CSF can indicate inflammation or infection in the brain and spinal cord."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26509-0
Short code
Neuts Band NFr CSF
Synonyms
Neuts Band NFr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like headaches, neck stiffness, fever, or confusion that could suggest a brain or spinal infection, such as meningitis or an abscess. It may also be used to monitor conditions affecting the central nervous system.

What to Expect Before the Test

You will likely have a lumbar puncture (spinal tap) to collect CSF. This involves lying on your side with your knees bent and inserting a needle into your lower back. The procedure is usually quick and done under sterile conditions.

What the Test Results Mean

High neutrophil counts in CSF often point to infections (like bacterial meningitis) or inflammatory conditions. Low counts may suggest viral infections, autoimmune diseases, or other neurological issues. Your results will be interpreted by a healthcare professional based on your symptoms and medical history.

Common Reasons for Testing

This test is commonly used to diagnose or monitor conditions like bacterial meningitis, brain abscesses, or other infections/inflammations in the central nervous system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Neutrophil CSF Count

Frequently asked questions

What does a high neutrophil count in CSF mean?
A high neutrophil count in CSF is most commonly associated with bacterial infections (e.g., bacterial meningitis) or abscesses. It may also appear in severe inflammatory conditions, though other cell types (like lymphocytes) usually dominate in viral infections or autoimmune responses.
What should I do if my neutrophil CSF count is abnormal?
If your test results show an abnormal neutrophil count, your healthcare provider will discuss your symptoms, medical history, and likely recommend further testing or treatment, such as antibiotics for infections or other targeted therapies. Follow their guidance closely.
Can lifestyle changes affect neutrophil CSF test results?
Lifestyle factors like diet or stress may influence overall immune response but are unlikely to directly alter CSF neutrophil counts. This test focuses specifically on the CSF environment, so lifestyle changes are less relevant unless they impact underlying conditions being evaluated.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy