Neutrophil count in cerebrospinal fluid (CSF) by manual differential cell count

Why This Test Is Done

Doctors may order this test if you have symptoms like severe headache, stiff neck, fever, or confusion, which could indicate an infection or inflammation in the central nervous system. It’s also used to monitor conditions like meningitis, encephalitis, or other neurological infections.

What to Expect During the Test

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). The sample is then examined under a microscope to count neutrophils among other cells. No special preparation is needed, but you may be asked to lie still for a short time afterward.

Possible Results and Interpretation

Normally, neutrophils in CSF are very low or absent. Elevated neutrophil counts may suggest bacterial infections, severe inflammation, or other conditions affecting the brain or spinal cord. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test is critical for diagnosing bacterial meningitis, abscesses in the brain or spinal cord, and other infections or inflammatory conditions in the central nervous system.