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Neutrophil Count in Blood (Qualitative Manual Differential)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates the proportion of neutrophils, a type of white blood cell, in your blood using a manual microscopic count. Neutrophils help fight infections.

Quick summary

["Neutrophils are key defenders against bacterial infections; their count helps assess immune response and infection risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71645-6
Short code
Neuts Band NFr.DF Fld Manual
Synonyms
Neuts Band NFr.DF Fld Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to diagnose or monitor conditions like infections (such as bacterial infections), inflammatory diseases, or certain blood disorders. It can also help evaluate how well your immune system is functioning or if you’re at risk for complications from infections.

How Is the Test Performed?

A small blood sample is taken from a vein, usually in your arm. The sample is then examined under a microscope by a trained technician to count and identify different types of white blood cells, including neutrophils, manually.

What Does the Result Mean?

Results are qualitative (descriptive rather than numerical), meaning they indicate whether the neutrophil count is elevated, low, or within expected ranges. For example, a higher-than-normal count may suggest infection or inflammation, while a lower count could indicate immune suppression or other conditions.

Common Conditions Monitored

This test is often used alongside other blood tests to diagnose or track conditions such as sepsis, chronic infections, autoimmune diseases, or neutropenia (a low neutrophil count). It helps guide treatment decisions, such as adjusting antibiotics or managing immune-related therapies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Neutrophil Differential (Manual Count)

Frequently asked questions

What might cause abnormal neutrophil levels?
Abnormally high neutrophil counts may occur with infections (like pneumonia or urinary tract infections), inflammation, or stress. Abnormally low counts could be due to infections, certain medications, autoimmune diseases, or blood disorders like leukemia. Always discuss your results with your healthcare provider.
How long does it take to get results?
Results from a manual differential test can take longer than automated tests, often 1–3 business days, depending on lab workload. Your provider will contact you once results are ready.
Can I eat or drink before this test?
No special preparation is needed for this test. However, if you’re on blood-thinning medication, let your provider know before the draw to avoid complications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy