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Neutrophil Segment Count in Whole Blood (Manual Differential)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections and inflammation.

Quick summary

["Neutrophils are key defenders against bacterial infections and help manage inflammation in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6745-4
Short code
Neuts Seg # Fld Manual
Synonyms
Neuts Seg # Fld Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to evaluate your immune system, check for infections, assess inflammatory conditions, or monitor treatment responses for conditions like leukemia, autoimmune diseases, or chronic infections.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re anxious, let your provider know—some people find it helpful to bring distractions or talk to a nurse.

What the Test Results Mean

Results show the percentage or absolute count of neutrophils in your blood. Abnormal levels (too high or too low) can signal infections, immune disorders, or other health issues. Your provider will discuss these with you based on your full medical picture.

Common Conditions Affecting Neutrophil Levels

High neutrophil counts may indicate infections (like bacterial), stress, or certain cancers. Low counts can suggest immune deficiencies, autoimmune diseases, or side effects from medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Neutrophil Count (Manual Differential)

Frequently asked questions

What causes my neutrophil count to be higher than usual?
Possible causes include infections (especially bacterial), chronic stress, certain medications, or inflammatory conditions. Your provider may also check for underlying conditions like leukemia or Cushing’s syndrome.
Can diet or lifestyle affect neutrophil counts?
Dietary factors (like high protein or vitamin deficiencies) or lifestyle habits (such as smoking or extreme stress) may indirectly influence immune function, but they don’t directly alter neutrophil counts. Focus on hydration and balanced nutrition for overall blood health.
How often should I get this test?
Frequency depends on your health needs. Your provider may order it periodically if you have chronic conditions (like autoimmune diseases) or if you’re undergoing treatment that affects your immune system.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy