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Neutrophil Segment Count (Absolute Neutrophil Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections by attacking bacteria and other harmful substances.

Quick summary

["Neutrophils are key defenders against infections; low or high counts may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33385-6
Short code
Neuts Seg NFr Plr
Synonyms
Neuts Seg NFr Plr
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like frequent or severe infections, unexplained fevers, or signs of an immune system issue. It could also be part of a routine blood check or monitoring for conditions like cancer or autoimmune disorders.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into a vein (often in your arm) to draw blood. If you’re nervous, let your healthcare provider know so they can help make it more comfortable.

What the Results Mean

Results show the absolute number of neutrophils per microliter of blood. A lower than expected count may indicate conditions like bone marrow disorders or immune deficiencies, while higher counts could signal infections, inflammation, or other health issues.

Common Conditions Affecting Neutrophil Counts

Low neutrophil counts (neutropenia) might be due to medications, certain cancers, or genetic disorders. High neutrophil counts (neutrophilia) can result from infections, stress, or inflammatory diseases. Your doctor will discuss these findings with you in detail.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

What causes a change in neutrophil levels?
Neutrophil counts can fluctuate due to infections (like bacterial illnesses), chronic illnesses (such as diabetes or inflammatory diseases), certain medications, or even stress. If your count is consistently low, it may signal an underlying condition that needs further investigation, such as a bone marrow disorder or autoimmune disease.
How often should I get this test?
The frequency depends on your health condition. If you have a chronic illness or are undergoing treatment, your doctor may order this test regularly to monitor your response to treatment or progression of your condition. If it’s part of a routine check, it may be done less often.
Can I take anything to prepare for this test?
No special preparations are needed, but avoid heavy meals before the test if you’re nervous about the needle. If you’re on blood-thinning medications, let your doctor know beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy