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Neutrophil Segment Count in Blood (Absolute Neutrophil Count, ANC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections.

Quick summary

["Neutrophils are key defenders against bacterial infections; low or high counts may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35012-4
Short code
Neuts Seg # Plr
Synonyms
Neuts Seg # Plr
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for infections, blood disorders, or immune system issues. It’s also used to monitor conditions like leukemia, autoimmune diseases, or after treatments like chemotherapy.

What to Expect Before the Test

No special preparation is needed. A simple blood draw from a vein (usually in your arm) is all that’s required. The process takes a few minutes, and you may feel slight discomfort.

What the Results Mean

Results are typically reported as a count of neutrophils per microliter (µL) of blood. While reference ranges vary by lab, very low counts may indicate infections, bone marrow disorders, or immune suppression, while very high counts could signal inflammation or infections.

Common Conditions Monitored

This test helps diagnose or manage conditions like severe infections, neutropenia (low neutrophil count), or conditions that affect white blood cell production.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Neutrophils play a critical role in fighting bacterial infections. Abnormal counts may signal underlying health issues, such as immune deficiencies, chronic illnesses, or reactions to medications.

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

What causes low neutrophil counts?
Low neutrophil counts (neutropenia) can result from infections, certain medications, autoimmune diseases, or conditions affecting bone marrow function. Severe cases may require medical attention to prevent infections.
What causes high neutrophil counts?
High neutrophil counts (neutrophilia) often occur during infections, inflammation, or stress. They can also appear in conditions like leukemia or certain autoimmune disorders.
How often should I get this test?
Your doctor will determine the frequency based on your health needs, ongoing treatments, or symptoms. Regular monitoring may be needed if you have chronic conditions or are undergoing treatments that affect white blood cells.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy