Skip to content

Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Urine

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called NGAL in your urine, which can help assess kidney function and detect early signs of kidney damage or injury.

Quick summary

["NGAL in urine helps monitor kidney health and identify potential kidney problems early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74103-3
Short code
NGAL SerPl IA.rapid-mCnc
Synonyms
NGAL SerPl IA.rapid-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like swelling in your legs, reduced urine output, or if you’re at higher risk for kidney issues, such as after surgery, trauma, or certain medical conditions. It can also be used to check for kidney problems in people with diabetes or high blood pressure.

What Does the Test Involve?

You’ll collect a small sample of your urine in a clean container. The sample is then sent to a lab where it’s analyzed to measure NGAL levels. No special preparation is usually needed, but you may be advised to avoid certain medications or foods before the test.

What Do Results Mean?

Higher than expected NGAL levels in urine may suggest kidney damage or stress, such as from infection, dehydration, or other health problems. Lower levels might indicate normal kidney function or conditions where NGAL isn’t typically released into urine.

How Is the Test Performed?

The test is quick and painless. You’ll likely urinate into the container provided, and the sample is processed immediately or stored for later analysis. The lab uses a sensitive method to detect NGAL, often through immunoassay.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine NGAL

Frequently asked questions

How soon after the test can I expect results?
Results are typically available within a few days, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
What are the most common causes of elevated NGAL levels?
Elevated NGAL levels can be caused by kidney damage from infections (like urinary tract infections), dehydration, kidney disease, or conditions that put stress on your kidneys, such as severe illness or injury.
Can I drink water before the test?
It’s usually fine to drink water before the test unless your provider advises otherwise. However, avoid excessive fluid intake just before collecting the sample to ensure a representative urine sample.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy