Neisseria gonorrhoeae Antigen Detection in Cerebrospinal Fluid by Immunoassay
This test checks for the presence of *Neisseria gonorrhoeae* bacteria in your cerebrospinal fluid (CSF), which may indicate meningitis caused by gonorrhea.
["Determines if gonococcal infection could be affecting your brain or spinal cord fluid."]
Key facts at a glance
- LOINC
- 27021-5
- Short code
- N gonorrhoea Ab Titr CSF CF
- Synonyms
- N gonorrhoea Ab Titr CSF CF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- comp-fix
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like severe headache, stiff neck, fever, or confusion, especially if you’ve been exposed to gonorrhea or have a known infection. It’s also used in certain cases of unexplained neurological symptoms or after a head injury.
What to Expect Before the Test
You’ll likely have a lumbar puncture (spinal tap) to collect the CSF. The procedure is quick but may cause temporary discomfort. No special preparation is needed, but inform your provider about any medications you’re taking.
What the Test Results Mean
A positive result means the test detected gonococcal bacteria in your CSF, which could indicate gonococcal meningitis. A negative result suggests no bacteria were found, but other causes of meningitis (like viral or bacterial infections) could still be present.
Possible Causes and Alternatives
If your test is negative but you still have symptoms, other infections (e.g., viral meningitis, tuberculosis, or other bacterial causes) may be investigated. Follow-up tests or cultures may be needed to identify the exact cause.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Gonococcal Antigen CSF Test
Frequently asked questions
What does gonococcal meningitis mean for my health?
How soon will I know my results?
Can I prevent gonococcal meningitis?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy