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Neisseria gonorrhoeae Antigen Detection (Genital Specimen)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of *Neisseria gonorrhoeae* bacteria, which can cause infections like gonorrhea in the genital area.

Quick summary

A positive result may indicate an active infection requiring treatment.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6489-9
Short code
N gonorrhoea Ag Genital Ql LA
Synonyms
N gonorrhoea Ag Genital Ql LA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
la
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like unusual discharge, pain during urination, or bleeding between periods. It’s also used for screening in high-risk groups or after exposure to gonorrhea.

What to Expect Before the Test

You’ll likely provide a sample from your genital area (e.g., urethra, cervix, or rectum) using a sterile swab. No special preparation is needed, but avoid bathing or using vaginal products 24 hours before.

What Happens During the Test

The swab is inserted gently into the affected area, and the sample is tested for bacterial antigens using a rapid immunoassay (often a color change result in 15–60 minutes).

Results and Next Steps

Results are typically available immediately. A positive test confirms gonorrhea and guides treatment (often antibiotics). A negative result means no detectable bacteria, but symptoms may still require further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Gonorrhea is a sexually transmitted infection (STI) caused by *Neisseria gonorrhoeae*. Untreated infections can lead to complications like pelvic inflammatory disease, infertility, or spread to other body parts (e.g., eyes, joints). Early detection and treatment are critical to prevent these risks.

Short name

Gonorrhea Test (Genital Swab)

Frequently asked questions

How soon can I expect results?
Results are usually available within 15–60 minutes, depending on the lab’s process. Follow-up instructions will be provided by your healthcare provider.
What if my test is positive?
If positive, you’ll need antibiotics to treat gonorrhea. Both you and your sexual partners should be tested and treated to prevent reinfection or spread. Avoid sexual contact until cleared.
Can I still have symptoms even if the test is negative?
Yes. A negative result means no detectable bacteria, but symptoms may persist due to other causes (e.g., untreated infections, irritation). If you have ongoing symptoms, see your provider for further evaluation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy