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Neisseria gonorrhoeae nucleic acid detection by probe (urine)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of bacteria that cause gonorrhea in your urine. It helps confirm if you or your partner may have been exposed to the infection.

Quick summary

["A simple urine test to detect gonorrhea infection quickly and accurately."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88224-1
Short code
N gonorrhoea DNA Anorectl Ql NAA+probe
Synonyms
N gonorrhoea DNA Anorectl Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a special probe to detect genetic material from *Neisseria gonorrhoeae*—the bacteria responsible for gonorrhea. A small urine sample is collected, and the probe identifies the bacteria’s DNA if present. This method is highly sensitive and can detect even small amounts of infection.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample, typically collected in a clean container at a clinic, lab, or during a medical exam. If you’re pregnant, inform your healthcare provider before testing.

Common Causes of Testing

Your doctor may recommend this test if you have symptoms like painful urination, discharge from the penis or vagina, or pelvic pain. It’s also used for screening during sexual health check-ups, especially if you’re at higher risk (e.g., new partners, sexually active teens).

Symptoms and When to Seek Help

Gonorrhea often causes symptoms in men (painful urination, discharge) and women (pelvic pain, unusual discharge). However, some women may have no symptoms. If you experience these signs, especially after unprotected sex, see a healthcare provider promptly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Gonorrhea urine test (qualitative PCR)

Frequently asked questions

Why is this test important?
Early detection of gonorrhea prevents complications like pelvic inflammatory disease (in women), infertility, or spread to other parts of the body (e.g., joints, heart). Untreated infections can also increase the risk of HIV transmission.
What does a positive result mean?
A positive result confirms gonorrhea infection. Treatment with antibiotics (like ceftriaxone or azithromycin) is essential to cure the infection and prevent further spread. Follow-up testing may be needed to ensure the infection is fully cleared.
What if I get a negative result?
A negative result means no detectable *Neisseria gonorrhoeae* DNA in your urine sample at this time. However, gonorrhea can sometimes be asymptomatic, so retesting after sexual exposure or symptoms develop is recommended. Other tests (e.g., cervical swab) may be needed if symptoms persist.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy