Neisseria gonorrhoeae nucleic acid detection by qualitative PCR (gonorrhea DNA test)
This test checks for the presence of genetic material from *Neisseria gonorrhoeae*, the bacteria responsible for gonorrhea, using a polymerase chain reaction (PCR) method. It helps confirm an infection that may not show symptoms.
["Detects gonorrhea bacteria even when symptoms are absent or mild."]
Key facts at a glance
- LOINC
- 43403-5
- Short code
- N gonorrhoea DNA Spec Ql Probe+sig amp
- Synonyms
- N gonorrhoea DNA Spec Ql Probe+sig amp
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-sig
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
A small sample of your bodily fluid—likely collected from the urethra, cervix, or rectum—is tested for genetic material from *Neisseria gonorrhoeae*. The PCR process amplifies and detects these DNA fragments to confirm infection, even in low quantities.
What to Expect Before the Test
No special preparation is needed. You may be asked to avoid sexual activity or certain medications (like antibiotics) for a short time before testing, depending on your healthcare provider’s instructions. Bring any recent medical records if you’ve had prior infections.
Common Uses and Who Might Need It
This test is typically ordered for people with symptoms of gonorrhea (e.g., painful urination, discharge) or those at higher risk (e.g., sexually active individuals with multiple partners, recent STI exposure). It may also be used as a screening test in certain clinical settings.
Results and Follow-Up
Results are usually available within 1–3 business days. If positive, follow your healthcare provider’s recommendations for treatment (often antibiotics) and retesting. If negative but you suspect infection, discuss further testing or retesting with your doctor.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Gonorrhea DNA Test (Qualitative PCR)
Frequently asked questions
Why is this test important?
How does this differ from culture tests?
Can I get this test at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy