Neisseria gonorrhoeae RNA Detection by Nucleic Acid Probe

How the Test Works

The test uses a specialized probe to identify genetic material (RNA) from *Neisseria gonorrhoeae*, the bacteria responsible for gonorrhea. A small sample of urine or vaginal fluid is collected and analyzed to detect the presence of this bacteria’s genetic material, which can confirm an infection even when symptoms are mild or absent.

What to Expect Before the Test

You may be asked to collect a urine sample or provide a vaginal swab, depending on your medical history and symptoms. No special preparation is needed, but inform your healthcare provider if you’re pregnant or have a history of allergies to testing materials.

When This Test Is Used

This test is typically ordered for sexually active individuals with symptoms like unusual discharge, pain during urination, or genital sores, as well as for routine screening in high-risk groups (e.g., sexually transmitted infection clinics). It can also be used to confirm a gonorrhea diagnosis in cases where culture results are unavailable or inconclusive.

What the Results Mean

A positive result means the test detected genetic material from *Neisseria gonorrhoeae*, strongly suggesting an active gonorrhea infection. A negative result means the test did not find this material, but other tests or follow-up may still be needed to rule out infection or other causes of symptoms.