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Neisseria gonorrhoeae nucleic acid detection by probe-based assay (urine)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of gonorrhea bacteria in your urine using a molecular probe. It helps confirm if you have an infection caused by *Neisseria gonorrhoeae*, which can affect the genitals, rectum, or throat.

Quick summary

["A positive result means gonorrhea may be present; further testing or treatment may be needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57289-1
Short code
N gonorrhoea rRNA Nph Ql NAA+probe
Synonyms
N gonorrhoea rRNA Nph Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a specialized probe to detect genetic material (DNA) from *Neisseria gonorrhoeae* in your urine. If bacteria are present, the probe binds to their DNA, triggering a signal that confirms infection. This method is highly sensitive and specific for gonorrhea.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample in a sterile container. Avoid urinating right before the test if possible, as it may dilute results. If you’re pregnant, inform your provider before testing.

What the Results Mean

A positive result indicates likely gonorrhea infection. A negative result means the test did not detect gonorrhea DNA, but other causes (like chlamydia) could still be present. Follow-up testing or treatment may be recommended.

When You Might Need This Test

Your healthcare provider may order this test if you have symptoms like unusual discharge, pain during urination, or genital sores, or if you’re at higher risk (e.g., sexually active without protection, recent sexual exposure).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Gonorrhea is a sexually transmitted infection (STI) that can cause serious health issues if untreated, including pelvic inflammatory disease, infertility, or spread to the blood or joints. Early detection and treatment are crucial to prevent complications.

Short name

Gonorrhea urine test (qualitative probe)

Frequently asked questions

Why did my provider recommend this test?
Your symptoms, risk factors, or recent exposure to gonorrhea prompted this test. It helps diagnose the infection quickly so you can receive appropriate treatment.
What does a positive result mean for my health?
A positive result means you likely have gonorrhea. Your provider will guide you on treatment options, which may include antibiotics. Always complete the full course to ensure the infection is fully cleared.
Can I still have sex while waiting for results?
No, it’s best to avoid sexual contact until you’ve received results and completed any prescribed treatment. Untreated gonorrhea can spread to others and worsen your health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy