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Neisseria gonorrhoeae nucleic acid detection by probe-based molecular assay (urine specimen)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Neisseria gonorrhoeae*, the bacteria responsible for gonorrhea, using a urine sample. It helps confirm if you have an infection that may require treatment.

Quick summary

["Detects gonorrhea infection quickly with a simple urine sample—no blood draw needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50412-6
Short code
N gonorrhoea rRNA Spec Donr Ql NAA+probe
Synonyms
N gonorrhoea rRNA Spec Donr Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like painful urination, discharge from the penis or vagina, or pelvic pain. It’s also used for screening in sexually active individuals, especially those with multiple partners or recent exposure to gonorrhea. Some doctors may order it during routine check-ups for sexually transmitted infections (STIs).

How the Test Works

The test uses a specialized probe to detect genetic material (DNA) from *N. gonorrhoeae* in your urine. This is a molecular method, meaning it looks for the bacteria’s unique genetic code rather than measuring its presence indirectly. The result is usually available within 24 hours or less.

Sample Collection

You’ll provide a urine sample, typically collected in a sterile container. No special preparation is needed, but avoid urinating for about an hour before the test if possible. The sample is then sent to a lab for analysis.

What to Expect After the Test

If you’re tested at a clinic or lab, you may receive results on the same day or within a few days. If you’re tested at home (e.g., a self-collection kit), follow the instructions carefully to ensure accuracy. If you get a positive result, your provider will guide you on next steps, including treatment options.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Gonorrhea DNA test (urine)

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 24 hours or less, depending on the lab’s processing time. If you’re tested at a clinic, you may get results on the same day. For home kits, check the instructions for turnaround time.
Can I still have sex while waiting for my results?
It’s safest to avoid sexual contact until you’ve received your results and your provider confirms you’re no longer infectious. If you’re unsure, ask your healthcare provider for guidance tailored to your situation.
What if I get a positive result? What happens next?
If your test is positive, your provider will prescribe appropriate antibiotics to treat the infection. You’ll likely need to return for follow-up testing to confirm the infection is cleared. They may also recommend testing for other STIs, like chlamydia, since gonorrhea and chlamydia often occur together.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy