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Neisseria gonorrhoeae RNA Nucleic Acid Detection (Urinary Probe)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from the bacteria *Neisseria gonorrhoeae* (gonorrhea) in your urine using a specialized molecular probe. It helps diagnose sexually transmitted infections (STIs) caused by gonorrhea.

Quick summary

["A quick, accurate way to detect gonorrhea in your urine, often used for early STI screening or confirmation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53927-0
Short code
N gonorrhoea rRNA Urth Ql NAA+probe
Synonyms
N gonorrhoea rRNA Urth Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a molecular probe to detect genetic material (RNA) from gonorrhea bacteria in your urine. This method is highly sensitive and can identify even small amounts of the bacteria’s genetic material, helping confirm an infection without growing cultures.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample, typically collected in a sterile container. If you’re pregnant or have a history of urinary tract issues, let your healthcare provider know before testing.

What to Expect After the Test

Results are usually available within 24 to 48 hours. If the test is positive, you’ll need treatment for gonorrhea, which may include antibiotics. Follow-up testing may be recommended to ensure the infection is cleared.

Why This Test Matters

Gonorrhea is a common STI that can cause serious health problems if untreated, including pelvic inflammatory disease, infertility, or spread to other parts of the body. Early detection and treatment help prevent complications and protect sexual partners.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Gonorrhea Urine Test

Frequently asked questions

Why was this test ordered?
Your healthcare provider may have ordered this test if you have symptoms of gonorrhea (e.g., unusual discharge, pain during urination) or if you’re at higher risk (e.g., sexually active without protection, recent STI exposure). It may also be used as part of routine screening for STIs in certain settings.
What does a positive result mean?
A positive result means the test detected genetic material from gonorrhea bacteria in your urine. This strongly suggests an active infection and requires immediate medical treatment with antibiotics to clear the infection.
What does a negative result mean?
A negative result means no genetic material from gonorrhea was detected in your urine sample. However, gonorrhea can sometimes be missed with a single urine test, so retesting may be recommended if you have ongoing symptoms or risk factors.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy