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Nucleic Acid Amplification Test for *Neisseria gonorrhoeae* RNA (Urinary Probe)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Neisseria gonorrhoeae*, the bacteria responsible for gonorrhea, using a urine sample.

Quick summary

["Helps diagnose gonorrhea quickly and accurately with a simple urine sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32199-2
Short code
N gonorrhoea rRNA Urth Ql Probe
Synonyms
N gonorrhoea rRNA Urth Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your healthcare provider may order this test to help identify an underlying condition, confirm a suspected diagnosis, or check how well a treatment is working. It gives your care team important information that helps guide decisions about your ongoing care.

Your healthcare provider may recommend this test if you have symptoms like painful urination, unusual discharge, or if you’re at higher risk for gonorrhea (e.g., sexually active, recent exposure). It’s also used for screening in sexually transmitted infection (STI) clinics or during pregnancy to prevent complications.

The test looks for specific markers in your body that can signal a particular health condition. Your sample is analyzed in a laboratory using validated methods, and the presence, absence, or amount of these markers helps your provider understand your health status.

The test uses a molecular method (PCR) to identify tiny amounts of gonorrhea bacteria’s genetic material in your urine. No blood draw is needed—just a urine sample is collected and tested in a lab.

Depending on the type of test, a small sample such as blood, urine, or a swab from the affected area may be needed. A trained healthcare professional will collect the sample, which usually takes only a few minutes, and then send it to the laboratory for analysis.

You’ll provide a midstream urine sample (a small amount of urine collected midstream during urination). Follow your provider’s instructions carefully to ensure accuracy.

Once the laboratory completes the analysis, your results are sent to your healthcare provider, who will explain what they mean for you. Results may be normal or abnormal, and your provider will discuss any follow-up testing, treatment, or monitoring you may need.

Results are typically ready within 1–2 days. A positive result means gonorrhea is likely present, while a negative result means it’s not detected in this sample. Follow-up testing or treatment may be recommended based on your symptoms and risk factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Gonorrhea Urine PCR

Frequently asked questions

This test is highly sensitive and specific for diagnosing gonorrhea, especially in asymptomatic individuals or those without obvious symptoms. Early detection allows for prompt treatment to prevent complications like pelvic inflammatory disease, infertility, or spread to others.
A positive result usually means the marker or condition the test was looking for was detected in your sample. Your healthcare provider will review the result along with your symptoms and medical history to confirm a diagnosis and recommend the appropriate next steps for your care.
A positive result confirms gonorrhea infection in your urine sample. You’ll need to see a healthcare provider for treatment with antibiotics tailored to the bacteria. Treatment may also include partners to prevent reinfection.
Yes, false negatives can occasionally happen, for example if the sample was collected too early, was not handled properly, or the marker level was too low to detect. If your symptoms continue even with a negative result, your provider may recommend repeating the test.
Yes, rare false negatives can occur if the sample isn’t collected properly or if the bacteria are present but not detected in this urine sample. If you have symptoms, repeat testing or other diagnostic methods may be needed.
The turnaround time depends on the type of test and the laboratory performing it. Many routine results are available within one to three days, while some specialized tests may take a week or longer. Your provider's office can give you an estimated timeline for your specific test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy