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Niacin (Vitamin B3) Serum Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of niacin (also called vitamin B3) in your blood serum. Niacin is an essential nutrient that helps your body convert food into energy and supports healthy skin, nerves, and digestion.

Quick summary

["Niacin helps your body use food for energy and supports important functions like nerve and skin health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
18244-4
Short code
Niacin SerPl-mCnc
Synonyms
Niacin SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test if you have symptoms like skin flushing, digestive issues, or if you’re being treated for conditions like high cholesterol or heart disease. It can also help check if you’re getting enough niacin through your diet or supplements.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re on niacin supplements, let your doctor know before the test.

What the Results Mean

Results show the niacin concentration in your blood, but exact values depend on factors like diet, supplements, and health status. Your doctor will interpret the result in relation to your overall health and symptoms.

Common Reasons for Testing

Doctors may test niacin levels to assess deficiencies (rare but possible in certain diets or malabsorption conditions), monitor supplement use, or evaluate metabolic health, especially in patients with liver or digestive disorders.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Niacin Level

Frequently asked questions

What does a low niacin level mean?
Low levels may indicate poor dietary intake, malabsorption issues, or certain metabolic disorders. Your doctor may recommend dietary changes, supplements, or further testing if needed.
What does a high niacin level mean?
High levels are less common but can occur with excessive niacin intake from supplements or certain medications. Symptoms like nausea or flushing may appear. Your doctor will guide next steps based on your symptoms and test results.
How often should I get this test?
This test is usually not routine unless you have symptoms, are taking niacin supplements, or have a known condition affecting niacin metabolism. Follow your doctor’s advice for follow-up testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy