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Nicotinamide (Vitamin B3) Concentration in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of nicotinamide, a form of vitamin B3, in your blood. Nicotinamide supports energy production and helps maintain healthy cells.

Quick summary

["Nicotinamide helps your body function properly, especially in energy metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25488-8
Short code
Nicotinamide SerPl-sCnc
Synonyms
Nicotinamide SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, skin issues, or digestive problems that could be linked to vitamin deficiencies. It may also be used to monitor vitamin B3 levels in certain medical conditions or treatments.

What to Expect Before the Test

No special preparation is needed. You may have blood drawn from a vein in your arm, similar to other blood tests. If you’re on a blood thinner, let your provider know before the test.

What the Results Mean

Results help determine if your vitamin B3 levels are within a healthy range. Low levels might indicate deficiencies, while high levels could be due to certain medications or conditions.

Common Causes of Abnormal Results

Low levels may be linked to poor diet, certain medications, or conditions affecting absorption. High levels could result from overconsumption of supplements or metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Nicotinamide is essential for DNA repair, energy metabolism, and maintaining healthy skin and nerves. Low levels may contribute to fatigue, neurological issues, or weakened immune function. Monitoring levels helps guide treatment for deficiencies or related conditions.

Short name

Nicotinamide Level

Frequently asked questions

What does a low nicotinamide level mean?
A low level may suggest a vitamin B3 deficiency, which could cause fatigue, skin changes, or digestive problems. Your provider may recommend dietary changes, supplements, or further testing.
Can diet affect nicotinamide test results?
Yes, your diet can influence levels. Eating foods rich in vitamin B3 (like chicken, fish, nuts, or fortified cereals) may help maintain healthy levels. Avoiding excessive alcohol or certain medications can also support normal results.
Are there any risks or side effects from this test?
The blood draw is generally safe but may cause mild discomfort or bruising at the site. Rarely, there could be a slight reaction to the needle. No other risks are expected from the test itself.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy