Fecal Immunochemical Test for Occult Blood (FIT) – High Sensitivity (DNA-based)
This test detects hidden (occult) blood in your stool using a DNA-based method to help screen for colorectal cancer or other gastrointestinal bleeding.
A simple stool test to check for hidden blood, which may signal potential health concerns like bleeding in the digestive tract.
Key facts at a glance
- LOINC
- 92901-8
- Short code
- NIP fet aneu microdel pnl Plas.cfDNA Seq
- Synonyms
- NIP fet aneu microdel pnl Plas.cfDNA Seq
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- sequencing
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test analyzes stool samples for DNA fragments associated with human blood. Unlike traditional chemical tests, this method is highly sensitive and specific, reducing false positives while improving accuracy for early detection.
What to Expect Before the Test
No special preparation is needed. Simply collect a small sample of stool in a provided container. If you’re using a kit, follow the instructions carefully to ensure accurate results. Avoid using laxatives or certain medications that could interfere with the test.
Common Uses and Benefits
This test is primarily used as a screening tool for colorectal cancer or to detect gastrointestinal bleeding. It’s often recommended for adults at average risk of colorectal cancer, though your doctor may suggest it based on your medical history or symptoms.
What the Results Mean
A positive result indicates the presence of occult blood, which may warrant further evaluation (such as a colonoscopy) to investigate potential causes like polyps, ulcers, or cancer. A negative result means no detectable blood was found in this sample, but it doesn’t rule out bleeding entirely.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
High-sensitivity FIT
Frequently asked questions
Why might my doctor order this test?
What if I have a positive result?
Can I take this test at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy