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Neutrophil count in whole blood (absolute neutrophil count, ANC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections by attacking bacteria and other harmful substances.

Quick summary

["Neutrophils are key defenders against bacterial infections; low or high counts may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98030-0
Short code
NK cyto IL2 Pnl Bld MC FC
Synonyms
NK cyto IL2 Pnl Bld MC FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for infections, monitor immune function, or evaluate conditions like leukemia, autoimmune diseases, or certain blood disorders. It’s also used before chemotherapy or other treatments that can affect your immune system.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into a vein (usually in your arm) to draw a blood sample. The process takes a few minutes, and you may feel a brief pinch. If you’re nervous, let your provider know.

What the Results Mean

Results are usually reported as a count of neutrophils per microliter of blood. A lower than normal count may indicate infection, bone marrow disorders, or immune suppression. A higher count could signal inflammation, infection, or other conditions. Your provider will discuss these results with you.

Common Conditions Affecting Neutrophil Counts

Conditions like severe infections (e.g., sepsis), certain cancers (e.g., leukemia), or autoimmune diseases (e.g., lupus) can alter neutrophil levels. Chronic illnesses, stress, or medications (like steroids) may also impact these cells.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Neutrophils are the body’s first responders to infections. Low neutrophil counts (neutropenia) can make you more vulnerable to infections, especially bacterial ones, while very high counts (neutrophilia) may signal ongoing inflammation or other underlying issues. Regular monitoring is important for patients undergoing treatments that suppress the immune system.

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and treatment plan. Your provider will let you know if you need this test regularly, such as monthly, every few weeks, or as needed for monitoring.
Will I feel any discomfort after the blood draw?
You might feel a slight bruise or soreness at the injection site, but most people don’t experience significant discomfort. Apply gentle pressure to the area afterward to help with healing.
Can I eat or drink before this test?
You can eat and drink normally unless your provider gives specific instructions. No fasting is required for this test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy